NgoLwesihlanu oluzayo, ifilimu yomndeni wonke enesihloko esithi "Ihhotela lezinja" lokho kusinikeza indaba enezingane nezilwane okuthi, ngokusho kwenganekwane yesinema, kuvame ukuthi kuthiwa awusebenzi nabo. Ngaphezu kwalokho, le filimu yenze kahle kakhulu ebhokisini ehhovisi e-US.
Ihhotela lezinja iyi-movie yomndeni ejabulisa kakhulu futhi emnandi ekhuluma ngendaba yezelamani ezimbili, U-Andi (Emma Roberts) noBruce (Jake T. Austin) abahlala endlini lapho izilwane zenqatshelwe khona, futhi abaphelelwa amasu okugcina uLwesihlanu, inja yabo elambile, ifihliwe. Lapho ngephutha bezithela phezu kwehhotela elishiyiwe, u-Andi uba nomqondo. Basebenzisa ithalente likaBruce lobuchule bokuguqula izinto zansuku zonke zibe izimangaliso zemishini, futhi ngosizo lwabangane bakhe abangomakhelwane, baguqula ihhotela le-ramshackle laba yipharadesi lezimilingo, hhayi ngoLwesihlanu kuphela, kodwa kuzo zonke izinja ezilahliwe abazitholayo. Kepha lapho izinja ezikhonkothayo zenza ukuthi omakhelwane nabasebenzi abangasebenzi ngokuzumayo ekheneli lendawo basole, u-Andi noBruce kufanele basebenzise yonke into abanayo ukuze babavimbe ekutholeni ukuthi ngubani ovumela izinja zingene.