Okunye okuzokhonjiswa okokuqala ngoLwesihlanu okulindeleke ukuthi wenze kahle kumabhokisi omdlalo wamahlaya waseMelika Ubheme kakhulu noSeth Rogen (ukungcola okuphoxayo) noJames Franco (indodana yeGreen Goblin eSpiderman) njengombhangqwana oyinhloko.
Le filimu ixoxa ngendaba kaDale Denton (Seth Rogen), umsebenzi wakhe okuwukunikeza ama-subpoena asemthethweni, uthenga insangu kumdayisi wezidakamizwa ogama lakhe linguSaul (James Franco) ngoba umdayisela uhlobo olusha lokhula olubizwa nge-"Pineapple Express" ngenhloso yokumhlonipha. kwisenzakalo somkhathi. USaul ufuna ukuba umngane kaDale, kodwa uDale uthanda ibhizinisi kuphela. Ngokuqondana nje, uDale uzibonela ngawakhe ukubulawa kwephoyisa elikhohlakele, uCarol Butler (Rosie Perez), kanye nomholi weqembu lezigelekeqe, uTed Jones (Gary Cole). Olunye ukhula lukaSawule lushiywe ngephutha endaweni yesigameko futhi bobabili kufanele babaleke eqenjini lezigebengu namaphoyisa.