Emva kweenyanga zamahemuhemu malunga nokubuya kwakhe, Inkampani yemveliso yeScreen Gems kunye nezitudiyo zakwaSony zibhengeze ukwenziwa kwesavenge esitsha sefranchise esekwe kumdlalo wevidiyo odumileyo woMhlali ombi.
Le iya kuba yi Inxalenye yesine yayo yonke i-zombie saga kunye nayo yonke into yakhomba kumdlali we-actress uMilla Jovovich ukuba abuyele eluswini luka-Alice onoburhalarhume.. Umboniso bhanyabhanya wokugqibela okhohlakeleyo wenziwa kwintlango ebhuqwa zii-zombies, kwaye isiphelo sasivuleleke ngokubanzi kwi-adventure entsha.
Ukubuyela phantse ngokuqinisekileyo kukaJovovich kufuneka songeze ukubuya kwe UPaul WS Anderson, ebandakanyeka ngendlela enye okanye enye kwenye kunye nefilimu nganye kwi-saga, ukususela walathisa eyokuqala waza kwezinye waba ngumlimi. UAnderson unxibelelane noonondaba ukuba Sele egqibile iskripthi seReident Evil 4 kwaye ulinde kuphela ukufumana umlawuli.
Abalandeli bacinga ukuba le nto intsha ka-Alice inokubizwa Ububi boMhlali: Emva kokufa, kunye nokuba iyelenqe liza kujikeleza ukunyanga okunokwenzeka kwentsholongwane ye-T. Imisebenzi yokuvelisa kwangaphambili ayikaqali, kodwa sele kuxeliwe ukuba Umhlali we-Evil 4 uya kukhutshwa nge-17 kaSeptemba 2010.